I'm not sure how much I like Kalonian Hydra in this deck, you really don't have many creatures with counters on them without the use of savage summoning. I think maybe Polukranos the World Eater would be a better choice, he can act as removal, and you have enough mana ramp to make him pretty scary with his monstrous ability. Plus just a 5/5 for 4 mana with no negative side effects.
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Black red vamps why no Falkenrath Aristotcrat?
No Blade of the Bloodchief?
Have you considered somberwald sage? he's probably my favorite mana grab creature
I could replace a few index's with some draw, but that makes descendant's path less effective, maybe two Garruks in place of two of the index. Although, some cheaper blue cards may be a better option to avoid screwing with my mana curve, or maybe i could cut 1 descendant's path, and one It that Betrays.I also getting a little concerned about how Garruk might interact with Call to Kindred, i think i might just replace Index with Ponder
Thanks for the suggestions, I've added two each of Quicksilver amulet, and Cryptic gateway, and taken out 2 awakening zones, 1 piper, and 1 descendant's path
I'll also have nest invader, and correct me if i'm wrong, but i believe that the eldrazi spawn creatures would also work as an eldrazi for descendant's path. I initially did have Mutavault in there, but it's a bit expensive, and i 'm too cheap to buy it. Thanks for the suggestion though