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There was a top deck awhile back that was speed black infect, so i decided to give a shot at it.
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Creature based infect decks tend to need to work with speed or recur, as in Mimic Vat or some such to throw Putrefax or some other infect over and over at the enemy. I think with the loss of Vampire's Bite after the Zendikar rolls out Mono Black Infect just wont hold up even for speed infect. I would suggest adding in Vampire's Bite and Mutagenic Growth, and perhaps Unholy Strength. Lashwrithe can be handy generally its too slow with the exception of that accidental win. The same goes for Core Prowler, often you will find yourself dropping your 3rd of 4th creature and having them removed/canceled and sitting without a single poison counter on the opponent at all, making all the prolif worthless. I would suggest gearing more towards the turn 3-5 win if you want to go speed infect. I am currently running an U/B prolif Infect myself and as a fan of infect it seems to be the only truly competitive version of Infect. Here is a link to the deck im running atm http://www.mtgvault.com/ViewDeck.aspx?DeckID=223500
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i tried to avoid it but i'll probably have to add mutagenic growth just to stay competitive but i'm going to try and keep this rotation ready so no vampire's bite, and from what i've played, the lashwrithe has actually worked very well. That's mainly because by then i have a plague stinger and my opponent thinks nothing of it. of course most of my firends don't play very aggro decks so that might be why. Thanks for the suggestions!