Nice. Though I don't care much for Dark Confidant... the whole life loss issue displeases me. Perhaps Jace's Archivist would be a better fit [with Jace's Erasure]. Pair it with Library of Leng so you don't lose your hand, and you still get the milling benefit.
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At any rate, (ya thief...:P)... do it right: http://www.mtgvault.com/ViewDeck.aspx?DeckID=201522
Gee, wherever did you think of this? :P
Absolutely beautiful :')
Personally, I'd run 4x Geth's Verdict instead of Doom Blade/GFTT, and 2x Hideous End. This way, they lose life in addition to losing a creature. As well, I'd run 4x Gatekeeper of Malakir, and would suggest you use these to replace your Bloodthrone Vampires or Child of Nights. (Neither really belong in this deck, you don't need to be sacrificing any vampires because it counter-acts what the Captivating Vampires do, and life gain is not this deck's primary focus. So ditch 'em. You might argue that it's necessary to sac your own vamps for Kalastria Highborn's ability... but you're only running 2x, and she's more of a "vampire life-insurance policy" than anything you could consider offensive. Gatekeeper of Malakir is a {B}{B} 2/2 and has a {B} kicker that causes target player to sac a creature when it enters the battlefield, which is more in-tune to what you're doing.) You might also consider replacing your Ichor Rats in your sideboard with a few Gruesome Encores instead. They are a great combo with Tainted Strike, since you are killing off your opponents creatures anyway... Why not bring them back to life under your control for one more go? Only this time with infect! Happy vamping! ;)
80 cards is heavy. I suggest trimming it down considerably.
I'm afraid Eilineas is correct. Final Punishment applies only to "damage" done, not "life lost". Whatever damage was dealt by the creature holding the Quietus Spike BEFORE the half-life loss trigger will be the only thing that Final Punishment deals.