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There are a few basic combos. Stuffy Doll and pariah\'s shield. Hit stuffy doll with shivan meteor for a whopping 13 damage directly to opponent. Isochron\'s scepter to lock in an extirpate or lightning blast, reuse extirpate as much as needed to remove unwanted cards. Welding jar, to require what has been cancled or countered. And of Course Underworld Dreams and Teferi\'s puzzlebox. Diabolic Tutor for fetch, chromatic sphe. for colorless energy transfer, and 4 blood crypts to even it out.
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It seems to me that Lightning Blast is a four cost spell and Isochron Scepter only copies two cost instants. I would sub in Lash Out or Lightning Bolt. With Lash Out you have the chance to hit for six and check out what the next card will be and get rid of it if you do not like it. And loose the Urza's so you do not get stuck waiting for the right color mana. Out side of that looks good to me.
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Yes, Isochron Scepter doesn't seem to be getting much use in your deck when you only have 1 spell (extirpate) to use it with. Also, your lands should follow your deck. You're gonna have a lot of trouble getting out enough mana for Underworld dreams. The underworld dreams + teferi's box combo is nice, but it doesn't follow your stuffy doll theme. Please comment on my Elemental Pandemonium deck http://www.mtgvault.com/viewdeck.php?did=7187